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2: Cortisol variation with age

We start with low doses and titrate slowly

The storage lesion is exacerbated in some categories of donors as a function of biology (sex, age) 21 , genetic traits 22,23,24,25 , and lifestyle-associated exposures 26 (comprehensively reviewed in 15,21,27,28

For GLA, that only happens through generous donors

The most common symptoms include [14]: Weight loss despite a higher appetite Heart palpitations Nervousness Tremors Difficulty breathing Fatigue Diarrhea or frequent bowel movements Muscle weakness Heat intolerance Sweating more than usual Irregular menstrual cycles Additional possible symptoms include [21]: Anxiety Irritability Difficulty sleeping Irregular heartbeat Goiter Erectile dysfunction or loss of libido Thyroid eye disease (eye bulging, tearing, dryness, irritation, puffy eyelids, inflammation, light sensitivity, blurred vision, pain) [14] Thick, red skin on the shins or tops of the feet How Common Is Hyperthyroidism